Complex Molecule Synthesis: From Challenge to Scale
Complex molecules are becoming increasingly important in modern drug discovery, especially in oncology, ADC payload-linker development, and highly potent small-molecule programs. However, their structural complexity often brings significant challenges in route design, stereochemical control, purification, and scale-up.
This makes integrated CDMO support a key driver for advancing complex molecule programs from development to scale.
Why Choose ChemExpress?
In complex molecule synthesis, success depends on technical expertise, experience, and platform integration. With over 20 years of CDMO experience, ChemExpress transforms complex synthetic challenges into efficient and commercially viable solutions.
Leveraging long-term expertise in building blocks, reference compounds, and biochemical reagents, ChemExpress has developed strong capabilities in complex molecule construction.
From route design and process optimization to scale-up and production, seamless integration significantly enhances efficiency, scalability, and delivery reliability.
ChemExpress has successfully achieved total synthesis of highly complex molecules, including:
Eribulin, often regarded as the “Mount Everest of small-molecule synthesis,” requires over 60 steps. Successful synthesis demonstrates industry-leading capabilities in complex molecule development and industrialization.
A comprehensive technology platform enables efficient synthesis and process development, including:
Supported by robust project management and GMP-compliant HPAPI facilities, ChemExpress can handle highly potent compounds up to OEB5 (OEL < 0.1 μg/m³), ensuring seamless transition from lab to industrial production.
If you are attending CPHI China 2026, don’t miss the opportunity to meet our experts in person and explore tailored solutions at Booth W4A02.
We look forward to seeing you there!
